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Drug discrimination is more pharmacologically particular than the tetrad, but also more time consuming. However, employed in tandem, the two approaches must be mutually useful for characterizing cannabinoids. It is noteworthy that the drug corporations Pfizer in the USA (Browne and Weissman, 1981; Weissman, 1978) and Janssen Pharmaceutica in Belgium (Colpaert, 2003, 2011) early on…